Dr Brooke Gardiner
Current Research Focus:
The Expression Genomics team has been actively colloborating with Applied Biosystems to apply short-read sequencing approaches to the study of the transcriptome. Dr Gardiner is currently managing the implementation of Next Generation Sequencing technology in the laboratory using the ABI SOLiD sequencing platform. This role involves co-ordinating the standardisation of instrument and library preparation procedures, as well as the development and optimisation of novel approaches for library generation. With a drive toward ensuring emerging technologies are accessible to the wider research community Brooke maintains a strong commitment to maintaining open interaction between both researchers and industry partners.
Background:
Brooke was awarded a Bachelor of Science from the University of Queensland in 1996. She completed her Honours under the direction of Dr Richard Sturm in 1998. Receiving a Queensland Cancer Fund PhD Scholarship she continued her research studies with Dr Sturm and was awarded a PhD in 2006. Her thesis, entitled "Investigation of the genetic events underlying the transition from radial to vertical growth phase in melanoma", focused on the transcriptional changes accompanying expression of the alpha v beta 3 integrin in melanoma.
Dr Gardiner commenced her first appointment in the Expression Genomics Laboratory in February 2003 as a Research Assistant. During her appointment she has been involved in a number of collaborative projects with a primary focus toward understanding the transcriptional regulation of kidney development and disease. During this time her research has relied predominantly on the use of microarray technologies as tools for the discovery of the transcriptional processes controlling the various systems under investigation.
In January of 2006 she commenced an appointment with the SRC to establish an array processing service using the Illumina BeadChip gene expression array technology. This service is now operational and available to both IMB staff and the wider Australasian scientific community. For details on submission and processing of microarray samples, as well as information about the further expansion of the SRC microaray facility services contact Dr Tina Maguire (Director SRC Microarray Facility) or visit http://microarray.imb.uq.edu.au/